OBJECTIVES:
To compare the effects of a single
nocturnal dose of 3 honey products (eucalyptus honey, citrus honey,
or labiatae honey) to placebo (silan date extract) on nocturnal cough
and difficulty sleeping associated with childhood upper respiratory
tract infections (URIs).
A survey was administered to parents
on 2 consecutive days, first on the day of presentation, when no
medication had been given the previous evening, and the following
day, when the study preparation was given before bedtime, based on a
double-blind randomization plan. Participants included 300 children
aged 1 to 5 years with URIs, nocturnal cough, and illness duration
of ≤7 days from 6 general pediatric community clinics. Eligible
children received a single dose of 10 g of eucalyptus honey, citrus
honey, labiatae honey, or placebo administered 30 minutes before
bedtime. Main outcome measures were cough frequency, cough severity,
bothersome nature of cough, and child and parent sleep quality.
In all 3 honey products and the
placebo group, there was a significant improvement from the night
before treatment to the night of treatment. However, the improvement
was greater in the honey groups for all the main outcome measures.
Parents rated the honey products
higher than the silan date extract for symptomatic relief of their
children’s nocturnal cough and sleep difficulty due to URI. Honey
may be a preferable treatment for cough and sleep difficulty
associated with childhood URI.
(doi: 10.1542/peds.2011-3075)
The researchers speculate that an
interaction between fibers that control cough and those that taste
sweetness may produce an antitussive effect. They conclude: "In
light of this study, honey can be considered an effective and safe
treatment [for nocturnal cough] of children >1 year of age."
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